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- Title
Factors Influencing Cognitive Function in Subjects With COPD.
- Authors
Dag, Ersel; Bulcun, Emel; Turkel, Yakup; Ekici, Aydanur; Ekici, Mehmet
- Abstract
BACKGROUND: The aim of this study was to assess the association between cognitive function and age, pulmonary function, comorbidity index, and the 6-min walk distance in subjects with COPD as well as to compare the Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) in terms of their ability to identify cognitive dysfunction in subjects with COPD. METHODS: A total of 52 individuals with stable COPD were included in this study. Cognitive function was assessed using MMSE and MoCA. Age, body mass index, the Modified Cumulative Illness Rating Scale, 6-min walk distance, arterial blood gases, and pulmonary function tests were assessed and recorded. RESULTS: The range and SD of scores in subjects with COPD were larger with MoCA than with MMSE. MMSE and MoCA scores are associated with 6-min walk distance and comorbidity index in subjects with COPD. General cognitive function measured by MoCA was negatively correlated with the comorbidity index but was positively associated with 6-min walk distance in subjects with COPD after controlling for possible confounding factors in the multivariate model. However, general cognitive function measured by MMSE was not correlated with the comorbidity index and 6-min walk distance in subjects with COPD, after controlling for possible confounding factors in the multivariate model. CONCLUSIONS: MoCA may be a more reliable screening test than MMSE in detecting cognitive impairment in subjects with COPD. The addition of cognitive tests on assessment of subjects with COPD can provide further benefit.
- Subjects
TURKEY; AGE distribution; BLOOD gases analysis; COGNITION; COGNITIVE testing; STATISTICAL correlation; OBSTRUCTIVE lung diseases; MULTIVARIATE analysis; SCIENTIFIC observation; REGRESSION analysis; PULMONARY function tests; STATISTICAL sampling; SEX distribution; STATISTICS; T-test (Statistics); COMORBIDITY; BODY mass index; DESCRIPTIVE statistics; MANN Whitney U Test
- Publication
Respiratory Care, 2016, Vol 61, Issue 8, p1044
- ISSN
0020-1324
- Publication type
Article
- DOI
10.4187/respcare.04403