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- Title
Inherited Variants of Genes Regulating Insulin Signaling and Lipogenesis Influence the Risk of Fibrosis in Nonalcoholic Fatty Liver Disease.
- Authors
Dongiovanni, Paola; Valenti, Luca; Rametta, Raffaela; Fracanzani, Anna Ludovica; Fargion, Silvia
- Abstract
The article discusses a study which assessed the role of well-characterized functional polymorphisms of genes involved in insulin signaling and lipogenesis on the risk of nonalcoholic fatty liver disease (NAFLD) progression to fibrosis. Subjects include patients with NAFLD, with liver biopsy and control groups. It concludes that genetic factors affecting lipogenesis and insulin signaling are associated with the progression of liver damage in NAFLD.
- Subjects
INSULIN; GENETIC polymorphisms; FATTY liver; FIBROSIS; LIVER diseases
- Publication
Diabetes, 2007, Vol 56, pA302
- ISSN
0012-1797
- Publication type
Article