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- Title
Chain reaction.
- Authors
Eisenstein, Michael
- Abstract
Reports on the description of a room-temperature reaction that could be performed in water to convert a phosphine and an azide to a corresponding primary amine and phosphine oxide by Hermann Staudinger in 1919 in Germany. Exploration of new methods to tag sugar molecules on cell surfaces; Introduction of functional groups that neither interfere with endogenous cellular functions nor be inappropriately recognized by the host; Significance of azide and phosphine for Staudinger reaction to take place.
- Subjects
GERMANY; CHEMICAL reactions; PHOSPHINE; AZIDES; CHEMICAL processes; AMINES; STAUDINGER, Hermann, 1881-1965; BIOTECHNOLOGICAL process control
- Publication
Nature Methods, 2004, Vol 1, Issue 1, p4
- ISSN
1548-7091
- Publication type
Article
- DOI
10.1038/nmeth1004-4b