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- Title
Synthesis and Biological Activities of 6-Hydroxyaurone Derivatives.
- Authors
Bao, Yong ‐ Tuan; Zhang, Min; Li, Ting; Xiao, Hui ‐ Feng; Zhao, Ting; Xu, Xiao ‐ Hua; Yang, Liu ‐ Qing
- Abstract
A series of 6-hydroxyaurone derivatives were synthesized in satisfactory yields and characterized by IR, 1H NMR, 13C NMR, and HRMS or elemental analysis. The structure of compound 3e was further confirmed by X-ray crystal analysis. Bioassay results indicated that some of the target compounds displayed moderate herbicidal activity against the dicotyledonous plant Brassica campestris L. at 100 µg·mL−1, and some compounds also showed significant antiproliferative activity against tumor cell lines Hela, HepG-2, and MCF-7.
- Subjects
CHEMICAL synthesis; NUCLEAR magnetic resonance; X-ray crystallography; TURNIPS; CELL lines; BIOLOGICAL assay
- Publication
Journal of Heterocyclic Chemistry, 2016, Vol 53, Issue 2, p637
- ISSN
0022-152X
- Publication type
Article
- DOI
10.1002/jhet.2497