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- Title
Nomogram for surgical hepatocellular carcinoma: What have we missed?
- Authors
Huo, Teh‐Ia; Ho, Shu‐Yein; Ko, Chih‐Chieh
- Abstract
Keywords: CC; nomogram; prognosis EN CC nomogram prognosis 3034 3035 2 12/24/21 20211201 NES 211201 To the Editor, We read with interest the paper 'Development of pre and post-operative nomograms to predict individual survival for ideal liver resection candidates with hepatocellular carcinoma' published in an upcoming issue of I Liver International i .1 It is an interesting study that specifically focused on the feasibility of nomograms in predicting long-term survival for patients with hepatocellular carcinoma (HCC) undergoing surgical resection. Notably, our recent study showed that 59% (308/522) of patients developed tumour recurrence within 5 years of resection.2 Therefore, tumour recurrence or cancer-free survival should be selected as the primary end point in this study. Firstly, in Zeng et al's study, overall survival (mortality) is the only end point for observation.1 However, since post-resection tumour recurrence is quite common for HCC, most liver surgeons and medical oncologists in liver cancer would agree that tumour recurrence is a more suitable primary end point for surgical HCC.
- Subjects
HEPATOCELLULAR carcinoma; NOMOGRAPHY (Mathematics); HEPATITIS B virus; CHRONIC hepatitis B
- Publication
Liver International, 2021, Vol 41, Issue 12, p3034
- ISSN
1478-3223
- Publication type
Article
- DOI
10.1111/liv.15071