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- Title
A Streamlined Synthesis of 2,3-Dihydrobenzofurans via the ortho-Quinone Methides Generated from 2-Alkyl-Substituted Phenols.
- Authors
Wu, Bo; Chen, Mu ‐ Wang; Ye, Zhi ‐ Shi; Yu, Chang ‐ Bin; Zhou, Yong ‐ Gui
- Abstract
A facile method for the stereoselective synthesis of trans-2,3-dihydrobenzofurans from ortho-quinone methides in situ generated from readily available 2-alkyl-substituted phenols using silver oxide-mediated oxidation has been developed. Additionally, the 2,3-dihydrobenzofurans can be further transformed into the aromatized 2,3-disubstituted benzofurans in the presence of DDQ.
- Subjects
QUINONE; ALKYL chlorides; PHENOLS; BENZOFURANS; OXIDATION
- Publication
Advanced Synthesis & Catalysis, 2014, Vol 356, Issue 2/3, p383
- ISSN
1615-4150
- Publication type
Article
- DOI
10.1002/adsc.201300830