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- Title
Harnessing imaging biomarkers for glioblastoma metastasis diagnosis: a correspondence.
- Authors
Jalloh, Mohamed; Kankam, Samuel Berchi
- Abstract
This document, titled "Harnessing imaging biomarkers for glioblastoma metastasis diagnosis: a correspondence," discusses the advancements in imaging biomarkers for the detection and monitoring of glioblastoma (GBM) metastasis. GBM is a type of brain tumor with a poor prognosis, and imaging techniques like magnetic resonance imaging (MRI) and computed tomography (CT) are commonly used for diagnosis. However, these techniques only provide anatomical information and may not capture the biological behavior of the tumor. Advanced MRI techniques, such as diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy (MRS), offer new avenues for understanding GBM. Additionally, positron emission tomography (PET) using radiotracers can provide functional information about tumor metabolism. Molecular MRI, deuterium metabolic imaging (DMI), and the integration of imaging biomarker data with other clinical and molecular data are also discussed as potential tools for improving GBM diagnosis and treatment. However, challenges such as standardization of imaging protocols, validation studies, and ethical considerations need to be addressed before these imaging biomarkers can be integrated into routine clinical practice.
- Subjects
COMPUTER-assisted image analysis (Medicine); GLIOBLASTOMA multiforme; METASTASIS; DIAGNOSIS; POSITRON emission tomography
- Publication
Journal of Neuro-Oncology, 2024, Vol 167, Issue 2, p365
- ISSN
0167-594X
- Publication type
Article
- DOI
10.1007/s11060-024-04606-5