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- Title
Efficacy of endoscopic trans-papillary gallbladder stenting and drainage in acute calculous cholecystitis in high-risk patients: a systematic review and meta-analysis.
- Authors
Malik, Adnan; Malik, Muhammad Imran; Amjad, Waseem; Javaid, Sadia
- Abstract
Background and aims: Acute calculous cholecystitis (ACC) represents about one-third of all surgical emergencies. The gold standard management of ACC is laparoscopic cholecystectomy. Although cholecystectomy is a safe procedure, it may be dangerous and contraindicated in patients with complex comorbidities. Endoscopic transpapillary gallbladder stenting (ETGBS) and drainage had been widely used to manage patients suffering from ACC with comorbidities. Methods: We searched PubMed, SCOPUS, Web of Science, and Cochrane Library for relevant studies assessing the use of ETGBS in patients suffering from ACC with various comorbidities. Risk of bias assessment was performed using the National Institues of Health (NIH) tool. We included the following outcomes: clinical success, technical success, late complications, and pancreatitis. Results: We included seven studies that met our inclusion criteria. We found that the pooled proportion of clinical success, technical success, late complications, and pancreatitis was [91.3%, 95% confidence interval (CI) (86.8%, 95.9%)], [92.8%, 95% CI (89%, 96.5%)], [5.4%, 95% CI (2.9%, 7.9%)], and [3.5%, 95% CI (1.2%, 5.8%)], respectively. Conclusion: We found that an ETGBS was an effective and well-tolerated method for the treatment of cholecystitis, especially in high-risk individuals.
- Subjects
ACALCULOUS cholecystitis; ONLINE information services; MEDICAL databases; META-analysis; CONFIDENCE intervals; SYSTEMATIC reviews; SURGICAL stents; TREATMENT effectiveness; GALLBLADDER; DESCRIPTIVE statistics; ENDOSCOPIC gastrointestinal surgery; MEDICAL drainage; MEDLINE; PANCREATITIS; ACUTE diseases; COMORBIDITY; PATIENT safety
- Publication
Therapeutic Advances in Gastrointestinal Endoscopy, 2023, p1
- ISSN
2631-7745
- Publication type
Article
- DOI
10.1177/26317745231192177