We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effects of 6 weeks of n-3 fatty acids and antioxidant mixture on lipid peroxidation at rest and postexercise.
- Authors
Filaire, E.; Massart, A.; Rouveix, M.; Portier, Hugues; Rosado, F.; Durand, D.
- Abstract
The purpose of this randomized study was to measure the influence of 6 weeks of LCPUFA (600 mg EPA and 400 mg DHA per day) supplementation alone or in association with 30 mg vitamin E, 60 mg vitamin C and 6 mg β-carotene on resting and exercise-induced lipid peroxidation in judoists (n = 36). Blood samples were collected at rest before (T (1)) and after the supplementation period, in preexercise (T (2)) and postexercise (T (3)) conditions, for analysis of α-tocopherol, retinol, lag phase (Lp) before free radical-induced oxidation, maximum rate of oxidation (R (max)) during the propagating chain reaction, maximum amount of conjugated dienes (CD(max)) accumulated after the propagation phase, and nitric oxide, malondialdehyde and lipoperoxide (POOL) concentrations. Dietary data were collected using a 7-day diet record. There were no significant differences among treatment groups with respect to habitual intakes of energy from fat, carbohydrate, or protein. At T (1), there were no significant differences among treatment groups with respect to lipid peroxidation, lag phase, and levels of α-tocopherol or retinol. The consumption of an n-3 LC PUFA supplement increased oxidative stress at rest and did not attenuate the exercise-induced oxidative stress. The addition of antioxidants did not prevent the formation of oxidation products at rest. On the contrary, it seems that the combination of antioxidants added to the n-3 LCPUFA supplement led to a decrease in, CD(max), R (max), and POOL and MDA concentrations after a judo training session.
- Subjects
FATTY acids; ANTIOXIDANTS; PEROXIDATION; MARTIAL artists; MALONDIALDEHYDE; NITRIC oxide; OXIDATIVE stress; HEALTH; THERAPEUTICS; COMBINATION drug therapy; COMPARATIVE studies; EXERCISE; MARTIAL arts; RESEARCH methodology; MEDICAL cooperation; LIPID peroxidation (Biology); OMEGA-3 fatty acids; PHYSICAL education; PLACEBOS; RELAXATION for health; RESEARCH; STATISTICAL sampling; TIME; VITAMIN A; VITAMIN E; EVALUATION research; RANDOMIZED controlled trials
- Publication
European Journal of Applied Physiology, 2011, Vol 111, Issue 8, p1829
- ISSN
1439-6319
- Publication type
journal article
- DOI
10.1007/s00421-010-1807-x