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- Title
Infratentorial C11orf95-fused gliomas share histologic, immunophenotypic, and molecular characteristics of supratentorial RELA-fused ependymoma.
- Authors
Keenan, Camille; Graham, Richard T.; Harreld, Julie H.; Lucas, John T.; Finkelstein, David; Wheeler, David; Li, Xiaoyu; Dalton, James; Upadhyaya, Santhosh A.; Raimondi, Susana C.; Boop, Frederick A.; DeCuypere, Michael; Zhang, Jinghui; Vinitsky, Anna; Wang, Lu; Chiang, Jason
- Abstract
DNA methylome profiling and transcriptome analysis have identified at least nine molecular groups of ependymoma separated by anatomical sites and molecular alterations [[6]]. While PF ependymomas with I C11orf95-RELA i fusions have been observed [[4]], it remains unclear whether they represent a distinct subset of ependymoma or are closely related to ST I RELA i -fused ependymomas, despite their infratentorial location.
- Subjects
CEREBELLAR tumors; PROGNOSIS; TUMORS in children
- Publication
Acta Neuropathologica, 2020, Vol 140, Issue 6, p963
- ISSN
0001-6322
- Publication type
Article
- DOI
10.1007/s00401-020-02238-3