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- Title
酵素分解蜂の子及びマカエキス末含有食品の継続摂取による 日本人健常成人の男性更年期症状,および勃起機能改善効果の検証
- Authors
伊藤隆志; 結石倫世; 浅間孝志; 奥村暢章; 八巻礼訓; 赤沼正德
- Abstract
Objectives: The aim of this study is to evaluate the effect of protease-digested Bee Larvae powder and Maca extract powder supplementation on aging males' symptoms and erectile function, and to assess their safety. Method: A single arm open-label clinical trial was conducted with healthy Japanese men. They were orally treated with protease-digested Bee Larvae powder and Maca extract powder for 12 weeks. The Aging Male Symptoms Score (AMS), International Index of Erectile Function (IIEF),Self-Rating Depression Scale (SDS),subjective symptoms of Fatigue Scale, Sleep Quality and stress were evaluated. A safety assessment was also performed based on the rate of side effects and based on an interview with a physician. The above measurements were performed at baseline, in the 4th, 8th and 12th weeks of the study. Results: We analyzed the results from 15 volunteers. The sexual score in AMS was significantly improved compared to the initial values. The improvements were confirmed in the erectile function score, the sexual satisfaction score and total score of IIEF15 compared to the initial values. In addition, the frequency of early morning erections (number/week) increased compared to the initial value. The subjective symptom of sleep quality was significantly improved compared to the baseline. No side effects were observed during the test. Conclusions: These results suggest that the protease-digested Bee Larvae powder and Maca extract powder supplementation is effective and safe in improving subjective sensation of AMS, erectile function, and quality of sleep in healthy Japanese adult men.
- Subjects
JAPANESE people; SEXUAL excitement; SYMPTOMS; MENTAL depression; POWDERS; PENILE erection
- Publication
Pharmacometrics / Ōyō Yakuri (0300-8533), 2020, Vol 99, Issue 3/4, p55
- ISSN
0300-8533
- Publication type
Article