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- Title
Biology under construction: in vitro reconstitution of cellular function.
- Authors
Liu, Allen P.; Fletcher, Daniel A.
- Abstract
We are much better at taking cells apart than putting them together. Reconstitution of biological processes from component molecules has been a powerful but difficult approach to studying functional organization in biology. Recently, the convergence of biochemical and cell biological advances with new experimental and computational tools is providing the opportunity to reconstitute increasingly complex processes. We predict that this bottom-up strategy will uncover basic processes that guide cellular assembly, advancing both basic and applied sciences.
- Subjects
CYTOLOGICAL research; MOLECULES; LIFE sciences; CONVERGENT evolution; CELL physiology
- Publication
Nature Reviews Molecular Cell Biology, 2009, Vol 10, Issue 9, p644
- ISSN
1471-0072
- Publication type
Article
- DOI
10.1038/nrm2746