We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Prostate-Specific Antigen Testing in Men Aged 40-64 Years: Impact of Publication of Clinical Trials.
- Authors
Goodwin, James S.; Tan, Alai; Jaramillo, Elizabeth; Yong-Fang Kuo
- Abstract
We assessed the impact of the publication of trials and changes in recommendations on the rates of prostate-specific antigen (PSA) screening in men aged 40 to 64 years by analyzing monthly medical claims for PSA testing in a commercial insurance data-base from 2001 to 2011, covering more than 1.5 million men in each year. The testing rates for men aged 40 to 49 years, 50 to 59 years, and 60 to 64 years were 12.1%, 32.7%, and 42.7%, respectively, in 2001 vs 15.7%, 34.2%, and 42.0%, respectively, in 2011. Men aged 40 to 49 years experienced a gradual increase in testing rate from 2001 through 2008 (annual change in PSA testing per 10 000 men [AC] = 4.37; P < .001), which became flat from mid-2009 through 2011(AC = -0.06; P=.98).The slope of PSA testing rates did not change in men aged 50 to 59 years or 60 to 64 years with the publication of the results of the large trials in 2009 or with the subsequent changes in recommendations on PSA testing.
- Subjects
PROSTATE-specific antigen; DIAGNOSIS; PROSTATE cancer; TUMOR antigen genetics; CANCER diagnosis; CLINICAL trials
- Publication
JNCI: Journal of the National Cancer Institute, 2013, Vol 105, Issue 10, p743
- ISSN
0027-8874
- Publication type
Article
- DOI
10.1093/jnci/djt039