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- Title
Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion following Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer: An Initial Experience.
- Authors
Doğanca, Tünkut; Argun, Ömer Burak; Tuna, Mustafa Bilal; Tüfek, İlter; Öbek, Can; Kural, Ali Rıza
- Abstract
Objective: To investigate the outcomes of robot-assisted radical cystectomy, intracorporeal urinary diversion, and extended lymph node dissection in patients with muscle-invasive bladder cancer who underwent neoadjuvant chemotherapy. Materials and Methods: A total of 14 patients underwent neoadjuvant chemotherapy for invasive bladder tumors, followed by robot-assisted radical cystectomy, extended lymph node dissection, and intracorporeal urinary diversion. Demographic, operative, and postoperative information of the patients was retrospectively evaluated. Gemcitabine plus cisplatin and cisplatin plus etoposide regimens were used as neoadjuvant treatments. Early and late-term complications were recorded. Results: In the early postoperative period (0-30 days), Clavien-Dindo grade 2 complications occurred in 6 patients and grade 3 complications in 2 patients. In the late postoperative period (31-90 days), Clavien-Dindo grade 2 complications occurred in 1 patient and grade 3 complications in 1 patient. The mean follow-up period was 15.5±5.7 months. Conclusion: Although the intracorporeal technique is more demanding in terms of learning and use, preoperative chemotherapy application should not be seen as a limitation in the application of this technique.
- Subjects
SURGICAL robots; CYSTECTOMY; BLADDER tumors; SKELETAL muscle; CANCER invasiveness; CISPLATIN; ANTINEOPLASTIC agents; TREATMENT effectiveness; RETROSPECTIVE studies; CANCER chemotherapy; ETOPOSIDE; SURGICAL complications; URINARY diversion; COMBINED modality therapy; MEDICAL records; ACQUISITION of data; GEMCITABINE
- Publication
Journal of Urological Surgery, 2024, Vol 11, Issue 2, p67
- ISSN
2148-9580
- Publication type
Article
- DOI
10.4274/jus.galenos.2023.2023-10-3