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- Title
A Human Immunodeficiency Virus Controller With a Large Population of CD4<sup>+</sup>CD8<sup>+</sup> Double-Positive T Cells.
- Authors
Durand, Christine M.; Buckheit III, Robert W.; Salgado, Maria; Pohlmeyer, Christopher W.; Walker-Sperling, Victoria E.; Hegarty, Robert W.; Ambinder, Richard F.; Blankson, Joel N.
- Abstract
Human immunodeficiency virus (HIV) controllers are patients who control viral replication without antiretroviral therapy. We present the case of an HIV controller who had CD4 and CD8 coexpressed on 40% of his T cells. Although a recent study found that double-positive T cells had superior antiviral capacity in HIV-1 controllers, in this case, the CD4+CD8+ T cells did not have strong antiviral activity.
- Subjects
T cells; HIV
- Publication
Open Forum Infectious Diseases, 2015, Vol 2, Issue 2, p1
- ISSN
2328-8957
- Publication type
Case Study
- DOI
10.1093/ofid/ofv039