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- Title
Quality of life in Sardinian patients with transfusion-dependent Thalassemia: a cross-sectional study.
- Authors
Floris, Francesca; Comitini, Federica; Leoni, GiovanBattista; Moi, Paolo; Morittu, Maddalena; Orecchia, Valeria; Perra, Maria; Pilia, Maria Paola; Zappu, Antonietta; Casini, Maria Rosaria; Origa, Raffaella
- Abstract
<bold>Purpose: </bold>The aim of this study has been to evaluate the physical, psychological, and social well-being in a large group of Sardinian adult patients with transfusion-dependent beta-Thalassemia when compared with a group of healthy subjects of the same age and geographical extraction.<bold>Methods: </bold>Male or female patients ≥ 18 years of age with Thalassemia major on regular transfusion at Thalassemia Center in Cagliari (Italy) were requested to complete the World Health Organization Quality of life-BREF (WHOQOL-BREF) questionnaire. The WHOQOL-BREF was also made available online to age- and sex-matched non-thalassemic adult subjects living in Sardinia.<bold>Results: </bold>Two hundred and seven subjects with Thalassemia were invited to participate in the study. The questionnaire was also completed by 211 age- and sex-matched non-thalassemic subjects living in Sardinia. Scores suggestive of a good quality of life were obtained in all the areas investigated. Thalassemia patients had scores at least as good as those of non-thalassemic subjects in all items and the percentage of those with a score ≥ 60 was higher among patients. The analysis of demographic actually highlights that the disease has a little effect on their personal and social lives. There was a positive association between subjective well-being and effective clinical conditions. Moreover, the association between health perception and adherence to treatment suggests that compliance with treatment contributes to the well-being of the patient, both physically and psychologically.<bold>Conclusions: </bold>Adult subjects with Thalassemia who live in Western countries have a good quality of life in accordance with the advances in the management of the disease.
- Subjects
THALASSEMIA; QUALITY of life; SARDINIANS; HEALTH outcome assessment; WELL-being
- Publication
Quality of Life Research, 2018, Vol 27, Issue 10, p2533
- ISSN
0962-9343
- Publication type
journal article
- DOI
10.1007/s11136-018-1911-7