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- Title
Maximizing the Kidney Donor Pool: Role of Expanded Criteria
- Authors
Chaudhary, Abhideep; Mehta, SN
- Abstract
There is critical shortage of organs for transplantation. It has led to consideration of alternative strategies to increase the donor pool. The use of expanded criteria donors can help lessen the current shortage of kidneys available for renal transplantation. No upper age limit for donors has accounted for a large measure of the increase in the organ donation rate. With the appropriate selection of organs from expanded donors, acceptable outcomes can be obtained. When living donors are selected properly, kidneys with anatomic variants without pathologic significance can be used safely as can be the donors with mild hypertension with normally functioning kidneys. Kidneys with a heightened potential for the development of progressive disease should not be considered for transplantation. Efforts to decrease the cold ischemia time by increasing the use of kidneys from expanded criteria donors may improve the outcome of transplantation further. Advances in surgical techniques and methods for predicting eventual long-term renal function in kidneys from expanded donors is thus critical in allowing precise selection criteria for kidneys for transplantation, resulting in the optimum use of a scarce and precious resource. This review summarizes the current guidelines for the use of expanded criteria, deceased and live donor kidneys for transplantation.
- Subjects
ORGAN donors; KIDNEY transplantation; MILD hypertension; HEALTH outcome assessment; GUIDELINES; DISEASE progression
- Publication
Apollo Medicine, 2008, Vol 5, Issue 4, p307
- ISSN
0976-0016
- Publication type
Article
- DOI
10.1016/S0976-0016(11)60156-7