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- Title
Angiographic Findings after Supplementation with Heracleum persicum Extract: Results of a Randomized Controlled Trial.
- Authors
Panahi, Yunes; Pishgoo, Bahram; Sahebkar, Amirhossein
- Abstract
Background: Heracleum persicum is a common dietary spice with several traditional medicinal properties important for cardiovascular health including antioxidant, hypolipidemic, and anti-infammatory effects. This study explored the effects of supplementation with H. persicum fruit on the angiographic findings of patients with minimal coronary artery disease (CAD). Methods: Subjects who were diagnosed with <50% stenosis in any of their coronary arteries by angiography were selected for this trial and randomly assigned to H. persicum hydroalcoholic fruit extract (n = 15; 300 mg/day) or placebo (n = 12) for 6 months. At the end of the trial, participants underwent a second coronary angiography in order to evaluate the progression of their disease. Results: Posttrial angiography did not reveal any improvement in the number of stenosed vessels after consumption of H. persicum extract versus placebo (P > 0.05). Similarly, there was no significant difference between the study groups in terms of disease progression and chest pain score (P > 0.05). Conclusions: The present results do not support any clinically significant benefit of supplementation with H. persicum extract on the angiographic findings of in patients with minimal CAD.
- Subjects
GIANT hogweed; CORONARY angiography; CORONARY disease; HERBAL medicine; RANDOMIZED controlled trials
- Publication
Heart Views, 2015, Vol 16, Issue 3, p85
- ISSN
1995-705X
- Publication type
Article
- DOI
10.4103/1995-705X.164462