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- Title
Special Issue: "Genomics of Stroke".
- Authors
Limborska, Svetlana A.; Filippenkov, Ivan B.
- Abstract
The role of another type of regulatory RNA - namely, circular RNAs (circRNAs), in cerebral ischemia conditions was studied by Filippenkov et al., as reported in their paper entitled "Genome-Wide RNA-Sequencing Reveals Massive Circular RNA Expression Changes of the Neurotransmission Genes in the Rat Brain after Ischemia-Reperfusion". Stroke is a multifactorial disease and an extremely serious and socially important medical condition [[1]]. The most common single-gene diseases connected with strokes are cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL); Fabry disease; mitochondrial myopathy, encephalopathy, lactacidosis, and stroke (MELAS); many single-gene diseases associated particularly with the cerebral small-vessel disease, such as COL4A1 syndrome, cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL), and hereditary endotheliopathy with retinopathy, nephropathy, and stroke (HERNS). The research articles in our SI are focused on association and functional studies of stroke-related genes or noncoding RNAs, and model systems, as well as pharmacogenomics and bioinformatics studies of stroke.
- Subjects
CIRCULAR RNA; HAPTOGLOBINS; GENOMICS; RETINOIC acid receptors
- Publication
Genes, 2022, Vol 13, Issue 3, p415
- ISSN
2073-4425
- Publication type
Article
- DOI
10.3390/genes13030415