ANALYSIS THE EFFECT OF MORINGA OLEIFERA PLANT EXTRACT ON THE TOXICITY OF CADMIUM CHLORIDE IN THE HEMATOLOGY OF THE CARP FISH, CYPRINUS CARPIO (L.1758).

Patel, Chandrakala; Hundet, Ajit

The present study was conducted to investigate the effects of Moringa oleifera plant extract (MPE) on the toxicity of cadmium chloride (CdCl2) in the hematology of carp fish Cyprinus carpio (Linnaeus 1758). For this the fish were exposed to two sub-lethal concentrations of CdCl² (specifically, 1.4 ppm and 2.8 ppm of LC50 value for a 96h), both in isolation and in combination with MPE (8 ml/L). Additionally, MPE (8 ml/L) was also administered independently during two exposure periods lasting 10 days and 20 days. Following the stipulated exposure period, blood samples were collected and assessed for alterations in hematological parameters, including the RBC and WBC counts, hemoglobin concentration (Hb), hematocrit (Hct) levels and erythrocyte indices, which encompass the mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC). The results of the study revealed that the groups exposed solely to CdCl2 displayed a concentration and time-dependent deterioration in the hematological profile of the fish. Conversely, the experimental group that received MPE (8ml/L) in conjunction with CdCl2 exhibited effective protection against CdCl2-induced toxicity thereby ameliorates the hematological alteration in the exposed fish. Moreover, the group exposed solely to MPE (8 ml/L) did not exhibit any notable variations in the hematological parameters when compared to the control group. Most of the hematological parameters in this group were closely resembled those of the control group. This study indicates that cadmium chloride (CdCl2) adversely affected the hematology of the fish, but the Moringa oleifera plant extract (MPE) successfully ameliorated CdCl2-induced hematological toxicity in carp fish, Cyprinus carpio. Thus, the result of the current finding suggests that Moringa oleifera plant extract (MPE) may offer effectiveness in mitigating the toxicity induced by CdCl2 in fish.

MORINGA oleifera; CADMIUM chloride; PLANT extracts; CARP; HEMATOLOGY; ERYTHROCYTES; BLOOD sampling

Journal of Experimental Zoology India, 2024, Vol 27, Issue 1, p227

0972-0030

Academic Journal

10.51470/jez.2024.27.1.227