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- Title
The Prevalence of Congenital Malformations and its Correlation with Consanguineous Marriages.
- Authors
Tayebi, Naeimeh; Yazdani, Katayon; Naghshin, Nazila
- Abstract
Objectives: Consanguinity has been a long standing social habit among some Iranians. This study is aimed at determining the role of consanguinity on congenital malformations and the correlation of inbreeding coefficient with anomalies. Methods: In this cross-sectional study, all the newborns who were born during 9 months period from April to December 2008. (n=1195) at Shahid Sadoughi hospital, Yazd, Iran were studied. Results: From 1195 neonates, 300 (25%) were from consanguineous marriages and 895 (75%) were from non-familial marriages. From 45 cases with anomalies, 34 (2.8%) cases were from familial marriages, while only 11 (0.9 %) cases were from non-familial marriages. There was a significant correlation between parental marriages and the prevalence of anomaly (p=0.018). Conclusion: The prevalence of congenital anomalies was mostly observed in consanguineous marriages compared to non consanguineous marriages.
- Subjects
IRAN; CONSANGUINITY; INBREEDING; HUMAN abnormalities; HUMAN embryo abnormalities; NEWBORN infants; DISEASE prevalence; INCEST; IRANIANS
- Publication
Oman Medical Journal, 2010, Vol 25, Issue 1, p1
- ISSN
1999-768X
- Publication type
Article
- DOI
10.5001/omj.2010.9