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- Title
ASSESSMENT OF ACUTE TOXICITY AND REPRODUCTIVE CAPABILITY OF A HERBAL COMBINATION.
- Authors
Riaz, Azra; Khan, Rafeeq Alam; Ahmed, Shadab; Afroz, Syeda
- Abstract
The drug under investigation is an herbal combination of Withania somnifera, Tribulus terrestris, Mucuna Pruriens and Argyreia speciosa which has been used for several years of its bio-stimulating, revitalizing and fertility enhancing effects. Present preclinical study is specifically designed to access the safety and efficacy of the product. The result of acute oral toxicity reveals that product is safe up to the dose of 5000mg/kg. The effects of study related to reproductive capability of drug on both sex reveals increase in reproduction rate up to two generations i.e. F0 and F1.
- Subjects
ACUTE toxicity testing; DRUG toxicity; WITHANIA somnifera; TRIBULUS terrestris; COWHAGE
- Publication
Pakistan Journal of Pharmaceutical Sciences, 2010, Vol 23, Issue 3, p291
- ISSN
1011-601X
- Publication type
Article