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- Title
EFFECT OF VITAMIN D ON INFECTION IN CHILDREN AGED 2-7 YEARS WHO ADMITTED TO OUR CLINIC WITH ACUTE BACTERIAL INFECTION.
- Authors
Sarı, Ahmet; Korğali, Elif Ünver
- Abstract
Purpose: Vitamin D deficiency is well-known to increase susceptibility to infections. Our aim in this study is to investigate whether bacterial infections in children have an effect on vitamin D levels. METHODS: Prospective study 70 children admitted to Cumhuriyet University Pediatrics Clinic between April and November 2016 were included. Children with chronic disease/liver-kidney failure/metabolic bone disease/malnutrition that will affect the level of vitamin D, those who have been using vitamin D/vitamin preparations for the last three months and who have been using antibiotics before the application have not been taken into study. Blood was drawn from the study group for antibiotic pre-treatment and on day 5 of treatment for D vitamins, WBC, lymphocyte, neutrophil, CRP, platelet levels and peripheral smear. The results of the control group were compared with the results of the study group before treatment and on the 5th day of treatment. SPSS 22 was used for analysis, p<0.05 was considered significant. Findings: Bacterial infections in our study group consist of tonsillopharyngitis, gastroenteritis, urinary system infection, soft tissue infection, pneumonia and sepsis. In our study, no statistically significant difference in age, sex, weight, height, head circumference between the patient group and the control group was found. The difference in infection parameters between the patient group and the control group was found to be statistically significant (p<0.05). Significant differences were detected between the infection markers of the study group and the infection markers of the control group before treatment and on the 5th day of treatment (p<0.05).There was no significant difference between the groups in terms of vitamin D levels both before treatment and on the 5th day of treatment, between the pretreatment and control groups, and between the 5th day of treatment and the control group. Conclusion: According to our study data, vitamin D was not affected by acute bacterial infections.
- Subjects
VITAMIN D deficiency; BACTERIAL diseases in children; CONTROL groups; BLOOD testing; DISEASE susceptibility
- Publication
Erciyes Medical Journal / Erciyes Tip Dergisi, 2018, Vol 40, Issue 1, pS8
- ISSN
2149-2247
- Publication type
Article