We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Prostate Cancer Stem Cells: Viewing Signaling Cascades at a Finer Resolution.
- Authors
Lin, Xiukun; Farooqi, Ammad; Qureshi, Muhammad; Romero, Mirna; Tabassum, Sobia; Ismail, Muhammad
- Abstract
It is becoming characteristically more understandable that within tumor cells, there lies a sub-population of tumor cells with 'stem cell' like properties and remarkable ability of self-renewal. Many features of these self-renewing cells are comparable with normal stem cells and are termed as 'cancer stem cells'. Accumulating experimentally verified data has started to scratch the surface of spatio-temporally dysregulated intracellular signaling cascades in the biology of prostate cancer stem cells. We partition this multicomponent review into how different signaling cascades operate in cancer stem cells and how bioactive ingredients isolated from natural sources may modulate signaling network.
- Publication
Archivum Immunologiae & Therapiae Experimentalis, 2016, Vol 64, Issue 3, p217
- ISSN
0004-069X
- Publication type
Article
- DOI
10.1007/s00005-016-0383-0