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- Title
Peripheral neuropathy in a copper-deficient goat.
- Authors
de Almeida, Valdir Morais; da Silva Chaves, Hisadora Advincula; da Silva Filho, Givaldo Bom; Pimentel Ribeiro, Danielle; Campelo Braga, Thaiza; de Souza Mendonça, Fábio
- Abstract
This report aimed to describe a case of peripheral neuropathy in a copper-deficient goat, and highlights the clinical, and pathological features of the disease. The goat had low body score, hyporexia, alopecia, achromotrichia, left hindlimb protraction, paralysis with dragging of digit and difficulty to stand up and microcytic normochromic anemia. Copper concentration in serum was markedly lower (2.0μmol L-1) whereas the iron serum content was significantly increased (51.0μmol L-1). The main gross alteration was the reduction of the quadriceps vastus laterallis muscle volume. Histologically, there was atrophy of the quadriceps vastus laterallis muscle and presence of satellite cells, infiltration of lymphocytes, macrophages and replacement of the fibers by connective tissue. In the femoral nerve, there was axonal degeneration with myelin sheath expansion and presence of vacuoles, usually in chains and containing axonal debris or macrophages. Clinical, laboratorial and pathologic findings are consistent with peripheral neuropathy due to a severy copper deficiency.
- Subjects
PERIPHERAL neuropathy; GOAT diseases; COPPER deficiency; DEFICIENCY diseases in domestic animals; PERIPHERAL neuropathy diagnosis; TREATMENT of peripheral neuropathy
- Publication
Ciência Rural, 2017, Vol 47, Issue 10, p1
- ISSN
0103-8478
- Publication type
Article
- DOI
10.1590/0103-8478cr20170248