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- Title
Molecular Toxicity of Popular Toothpaste Formulations on Post-Juveniles of Clarias gariepinus.
- Authors
OGUNWOLE, G. A.; KOLAWOLE, Y. F.; AYIBIOWU, T. E.; OYEWOLE, O. A.
- Abstract
The widespread use of toothpaste containing various chemical formulations has raised concern regarding their potential impact on aquatic ecosystems. This research examines the molecular toxicity of popular toothpaste brands on post-juveniles of Clarias gariepinus from a commercial fish farm in Akure, Ondo State, Nigeria. Specifically assessing the impact of these toothpaste brands on the mRNA expression levels of the heat shock protein (HSP70), interleukin (IL-1β), melatonin receptors (MEL1C), and growth hormone in comparison to a control group. The results revealed a significant upregulation of HSP70, IL-1β, and MEL1C genes in the exposed group, indicating a potential stress response and immune system activation. Intriguingly, the growth hormone mRNA expression remained unaffected in the treated group compared to the control. These findings underscore the need for further exploration into the potential molecular consequences of common toothpaste ingredients on aquatic organisms, raising important questions about environmental safety and consumer product development.
- Subjects
AKURE (Nigeria); NIGERIA; CLARIAS gariepinus; SOMATOTROPIN receptors; TOOTHPASTE; HEAT shock proteins; CONSUMER goods; FISHERIES; FISH farming
- Publication
Journal of Applied Sciences & Environmental Management, 2024, Vol 28, Issue 4, p1151
- ISSN
1119-8362
- Publication type
Article
- DOI
10.4314/jasem.v28i4.14