We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Refractory chronic spontaneous urticaria after heterologous COVID-19 booster vaccination.
- Authors
Tomaras, Miranda Crista; Douglas, Leah Michelle; Schmidt, Rosa Michelle; Bloomquist, Maria Suzanne; Diwan, Abdul Hafeez; Soo Jung Kim
- Abstract
Chronic spontaneous urticaria (CSU) involves recurrent, pruritic wheals lasting more than 6 weeks in response to various etiologies, including unknown causality. Though most cutaneous reactions to the COVID-19 vaccine series are self-limited and of short duration, more complex presentations including chronic spontaneous urticaria have been described. To the best of our knowledge, this is the first report of chronic spontaneous urticaria following heterologous mRNA COVID-19 booster vaccination that includes vaccination with both forms of the mRNA vaccine. Our patient received Pfizer-BioNTech for the primary series and Moderna for the booster. After failing several therapies, our patient's urticaria was refractory even to omalizumab. The source for chronic spontaneous urticaria development in our patient may be related to the unique humoral response elicited by receipt of a different mRNA vaccine manufacturer.
- Subjects
URTICARIA; CHRONIC diseases; COVID-19 pandemic; VACCINATION; ETIOLOGY of diseases; PFIZER Inc.
- Publication
Dermatology Online Journal, 2024, Vol 30, Issue 2, p1
- ISSN
1087-2108
- Publication type
Article
- DOI
10.5070/D330263591