We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Safety and efficacy of atrial fibrillation ablation guided by Ablation Index module.
- Authors
Solimene, Francesco; Schillaci, Vincenzo; Shopova, Gergana; Urraro, Francesco; Arestia, Alberto; Iuliano, Assunta; Maresca, Fabio; Agresta, Alessia; La Rocca, Vincenzo; De Simone, Antonio; Stabile, Giuseppe
- Abstract
<bold>Purpose: </bold>Reconnection of pulmonary veins (PVs) remains common following radiofrequency catheter ablation for atrial fibrillation (AF). Ablation Index (AI) is a novel ablation quality marker that incorporates stability, contact force (CF), time, and power in a weighted formula. Its use seems to improve lesion durability. This is a prospective, single-arm registry to investigate on the safety and mid-term efficacy of AF ablation guided by the AI.<bold>Methods: </bold>One hundred fifty-six consecutive patients (mean age 58 ± 10 years, 49% males, 44% with structural heart disease) referred for paroxysmal (124) or persistent (32) AF underwent antral PV isolation using a surround flow CF-sensing catheter guided by the AI. Radiofrequency was delivered targeting interlesion distance ≤ 6 mm and Ablation Index of 330-350 at posterior wall and 400-450 at anterior wall.<bold>Results: </bold>Mean overall procedure time was 95 ± 30 min with a mean fluoroscopy time of 5 ± 6 min. Mean ablation time was 26 ± 10 min, 627/628 targeted PV were isolated. One pericardial effusion and two groin hematomas were reported; none required intervention. During a mean follow-up of 14 ± 6 months, 17 (10.8%) (9% paroxysmal AF vs 22% persistent AF, p = 0.09) patients had an atrial arrhythmia recurrence.<bold>Conclusions: </bold>PV ablation guided by AI resulted feasible, achieving a high rate of isolated PVs, with a low complication rate, and allowed a high single-procedure arrhythmia-free survival at 14 months.
- Subjects
ATRIAL fibrillation; CATHETER ablation; PULMONARY veins; HEART diseases; HEMATOMA
- Publication
Journal of Interventional Cardiac Electrophysiology, 2019, Vol 54, Issue 1, p9
- ISSN
1383-875X
- Publication type
journal article
- DOI
10.1007/s10840-018-0420-5