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- Title
Usefulness of Toxoplasma gondii recombinant antigens (GRA1, GRA7 and SAG1) in an immunoglobulin G avidity test for the serodiagnosis of toxoplasmosis.
- Authors
H. Pietkiewicz; E. Hiszczy?ska-Sawicka; J. Kur; E. Petersen; H. Nielsen; M. Paul; M. Stankiewicz; P. Myjak
- Abstract
Abstract??The precise diagnosis of an acute and recentToxoplasmainfection in pregnant women and the newborn child is important before treatment. This study describes a newToxoplasma gondiiIgG avidity test based on a combination of recombinant GRA1, GRA7 and SAG1 antigens and shows that this test is useful for diagnostic purposes and may replace the lysed, whole-cell antigens. Although more sera need to be tested, the results obtained here suggest that the IgG avidity test performed with rec-antigens correlated more with the stage of aT. gondiiinfection than the IgG avidity results obtained with the lysed, whole-cell antigen test, the VIDAS Toxo IgG avidity (bioM?rieux).
- Subjects
TOXOPLASMA gondii; RECOMBINANT antibodies; IMMUNOGLOBULIN G; TOXOPLASMOSIS
- Publication
Parasitology Research, 2007, Vol 100, Issue 2, p333
- ISSN
0932-0113
- Publication type
Article
- DOI
10.1007/s00436-006-0265-1