We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Trial watch: Clinical trial boost for lentiviral gene therapy.
- Authors
Flight, Monica Hoyos
- Abstract
The article focuses on the two Phase I/II studies which emphasize the potential of the utilization of lentiviral vectors in haematopoetic stem cell (HSC) gene therapy. It says that the three presymptomatic children who have metachromatic leukodystrophy (MLD) were included in the first trial. It adds that the method used by Naldini and colleagues in the first study was also used in the second trial for the treatment of the three children with Wiskott-Aldrich syndrome (WAS).
- Subjects
LENTIVIRUSES; STEM cells; GENE therapy; METACHROMATIC leukodystrophy; WISKOTT-Aldrich syndrome; CLINICAL trials; THERAPEUTICS
- Publication
Nature Reviews Drug Discovery, 2013, Vol 12, Issue 9, p654
- ISSN
1474-1776
- Publication type
Article
- DOI
10.1038/nrd4111