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- Title
A - 154 Neuropsychological Profile of a Patient Post Anoxic Brain Injury with Balint Syndrome: a Case Study Five Years Post-Injury.
- Authors
Moncivais, Jacqueline A; Piszczor, Justyna; Yang, Jessica; Fink, Joseph W
- Abstract
Objective: Cerebral anoxia is the absence or near absence of oxygen in the brain's arterial blood supply. One cause of cerebral anoxia is acute cardiorespiratory failure, which, if left untreated, can lead to brain tissue necrosis, causing an anoxic brain injury (AnBI). AnBI causes a range of motor and cognitive deficits, though long-term (> 2.0 years) neuropsychological sequelae of AnBI are not well understood. Method: A 66-year-old female presented for a neuropsychological evaluation 5.4 years status post myocardial infarction complicated by cardiac arrest requiring cardiopulmonary resuscitation (CPR) for one hour. The patient was comatose for two weeks and initially exhibited a 20-year- retrograde amnesia (RA). She reportedly reached a cognitive plateau approximately 2.5 years after the original insult. 4.9 years after the original insult, a new emergence of severe functional impairment was observed. Relevant medical history was significant for hypertension, hypocholesterolemia, and coronary artery disease. Neuroimaging revealed mild cortical atrophy and mild microvascular ischemia. Results: Her neurocognitive profile demonstrated impairments in all assessed cognitive domains. Her MMSE score declined 11 points in 2 months. Behavioral observations and assessment findings demonstrated features of Balint's Syndrome (e.g., optic apraxia, optic ataxia, simultanagnosia). Conclusions: The patient's AnBI was severe, given multiple markers: CPR duration, coma length, and RA. Moreover, her decline in functional ability demonstrates that a resurgence of functional impairment 5.4 years status post a severe AnBI is possible, highlighting the importance of neuropsychological monitoring over time.
- Subjects
BRAIN injuries; CEREBRAL anoxia; SYNDROMES; NEUROPSYCHOLOGICAL tests; CEREBRAL atrophy; COMA; CEREBELLUM degeneration
- Publication
Archives of Clinical Neuropsychology, 2023, Vol 38, Issue 7, p1326
- ISSN
0887-6177
- Publication type
Case Study
- DOI
10.1093/arclin/acad067.171