We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Evaluation of three immunochromatographic tests in COVID-19 serologic diagnosis and their clinical usefulness.
- Authors
Pegoraro, Manuela; Militello, Valentina; Salvagno, Gian Luca; Gaino, Stefania; Bassi, Antonella; Caloi, Cecilia; Peretti, Angelo; Bizzego, Silvia; Poletto, Laura; Bovo, Chiara; Lippi, Giuseppe; Lo Cascio, Giuliana
- Abstract
Results of three rapid immunochromatographic tests (ICTs) were compared with those obtained with two automated immunoassays for evaluation of their usefulness. One hundred fifty-nine patients and 67 healthy volunteers were included. Different assays demonstrate 41–45% of diagnostic sensitivities and 91–98% of specificities, with substantial agreement (89.3–91.2%), but a high percentage of weak positive results (13–22%) was observed with ICTs. ICTs performances were comparable to those of automated immunoassays. ICTs could have a role as screening approach due to their easy usability. Subjective interpretation, significant rate of uncertain results, uncertainty on viral antigens source are undoubtedly drawbacks.
- Subjects
SERODIAGNOSIS; COVID-19 testing; VIRAL antigens; COVID-19; IMMUNOASSAY; SARS-CoV-2
- Publication
European Journal of Clinical Microbiology & Infectious Diseases, 2021, Vol 40, Issue 4, p897
- ISSN
0934-9723
- Publication type
Article
- DOI
10.1007/s10096-020-04040-1