We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Normal fat intake with high MUFA content and an appropriate SFA/MUFA/PUFA ratio improved the health of rats.
- Authors
Zhou, Yuhao; Yang, Ligang; Chu, Chu; Chen, Shiqing; Yue, Danwei; Hao, Yoong Jun; Sun, Guiju; Xia, Hui
- Abstract
The quantity and quality of dietary fats have a significant impact on human health. This study aimed to investigate the effects of different cooking oils (olive oil (OO), soybean oil (SO), and blended oil (BO)) on growth, glucolipid metabolism, inflammation, and oxidative stress of rats fed normal and high‐fat diets. The results showed that the OO‐fed group had lower concentrations of serum triglyceride (TG), low‐density lipoprotein cholesterol (LDL‐C), malondialdehyde (MDA), oxidized LDL‐C (ox‐LDL‐C), and serum total cholesterol (TC) than the normal‐fat SO‐fed group, and rats in the BO‐fed group had lower values of serum interleukin‐6 (IL‐6), high‐sensitivity C‐reactive protein (hs‐CRP), tumor necrosis factor (TNF‐α), and nonesterified fatty acids (NEFA) than the normal‐fat SO‐fed groups. However, higher serum glutathione peroxidase (GSH‐Px) activity was observed in the OO‐fed group, while those fed with BO had higher serum superoxide dismutase (SOD) and GSH‐Px activities. Generally, most health‐beneficial fatty acid profiles have a high content of monounsaturated fatty acids (MUFAs), an appropriate saturated fatty acid (SFA)/MUFA/poly unsaturated fatty acid (PUFA) ratio, and a low n‐6/n‐3 PUFA ratio, while diets contained a high content of fat is detrimental to health.
- Subjects
EDIBLE fats &; oils; FREE fatty acids; FAT; MONOUNSATURATED fatty acids; SATURATED fatty acids; UNSATURATED fatty acids; GLUTATHIONE peroxidase
- Publication
European Journal of Lipid Science & Technology, 2024, Vol 126, Issue 6, p1
- ISSN
1438-7697
- Publication type
Article
- DOI
10.1002/ejlt.202300214