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- Title
Editorial: Mitochondrial Dynamics in Endocrine Physiology and Disease.
- Authors
Poderoso, Cecilia; Filippi, Beatrice Maria; Maloberti, Paula Mariana; Franco, Maria Clara
- Abstract
Keywords: mitochondrial fusion; mitochondrial fission; neurodegenerative diseases; mitochondrial metabolism; endocrine system; cellular metabolism EN mitochondrial fusion mitochondrial fission neurodegenerative diseases mitochondrial metabolism endocrine system cellular metabolism 1 2 2 02/18/22 20220216 NES 220216 Mitochondria are important energy sensors; they modulate their activity to meet the energy demands of the cell. A set of mitochondria-shaping proteins control mitochondria dynamics and determine whether fusion or fission will occur. In particular, Chang et al. used cybrid B4 cells harboring a diabetes-susceptible mitochondrial DNA haplogroup to demonstrate that the insulin sensitivity of these cells was altered by changes in mitochondria dynamics.
- Subjects
TYPE 2 diabetes; ENDOCRINE diseases; MITOCHONDRIA; STEROIDOGENIC acute regulatory protein; MITOCHONDRIA formation
- Publication
Frontiers in Endocrinology, 2022, Vol 13, p1
- ISSN
1664-2392
- Publication type
Editorial
- DOI
10.3389/fendo.2022.844842