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- Title
Molecular Typing on Human Blood Reveals the Borrelia afzelii Infection in Korea.
- Authors
Yeon-Sook Kim; Jeoungyeon Kim; Yeon-Joo Choi; Taeuk Kang; Hye-Jin Park; Won-Jong Jang
- Abstract
Lyme disease is a tick-borne infection in Korea. Here, clinical samples were collected from a 72-year old patient, with sudden onset of fever on April, 2018. The patient was passed away after 3rd day of doxycycline administration. The molecular diagnostic tests, nested polymerase chain reaction targeting 5S-23S rRNA intergenic spacer region (IGS) and multilocus sequence typing (MLST), showed positive for Borrelia afzelii from blood. Further, mutations in both 5S - 23S IGS and pepX allele of MLST were determined. Herein, we report the expected first death case by B. afzelii infection in Korea.
- Subjects
SOUTH Korea; LYME disease; BORRELIA; BLOOD grouping &; crossmatching; POLYMERASE chain reaction; TICK-borne diseases; OLDER patients
- Publication
Infection & Chemotherapy, 2023, Vol 55, Issue 4, p500
- ISSN
2093-2340
- Publication type
Article
- DOI
10.3947/ic.2023.0094