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Activation of transient receptor potential channel Sm.(Schistosoma mansoni)TRPMPZQ by PZQ, enhanced Ca++ influx, spastic paralysis, and tegumental disrupture—the deadly cascade in parasitic schistosomes, other trematodes, and cestodes.
Published in:
Parasitology Research, 2020, v. 119, n. 8, p. 2371, doi. 10.1007/s00436-020-06763-8
By:
- Harder, Achim
Publication type:
Article
In vitro efficacy of cyclooctadepsipepdtides and aminophenylamidines alone and in combination against third-stage larvae and adult worms of Nippostrongylus brasiliensis and first-stage larvae of Trichinella spiralis.
Published in:
Parasitology Research, 2013, v. 112, n. 1, p. 335, doi. 10.1007/s00436-012-3141-1
By:
- Kulke, Daniel;
- Krücken, Jürgen;
- Demeler, Janina;
- Harder, Achim;
- Mehlhorn, Heinz;
- Samson-Himmelstjerna, Georg
Publication type:
Article
The Putative Cyclooctadepsipeptide Receptor Depsiphilin of the Canine Hookworm Ancylostoma caninum.
Published in:
Parasitology Research, 2009, v. 105, n. 0, p. 91, doi. 10.1007/s00436-009-1500-3
By:
- Krüger, Nina;
- Harder, Achim;
- von Samson-Himmelstjerna, Georg
Publication type:
Article
Standardization of the egg hatch test for the detection of benzimidazole resistance in parasitic nematodes.
Published in:
Parasitology Research, 2009, v. 105, n. 2, p. 1, doi. 10.1007/s00436-009-1466-1
By:
- von Samson-Himmelstjerna, Georg;
- Coles, Gerald C.;
- Jackson, Frank;
- Bauer, Christian;
- Borgsteede, Fred;
- Cirak, Veli Y.;
- Demeler, Janina;
- Donnan, Alison;
- Dorny, Pierre;
- Epe, Christian;
- Harder, Achim;
- Höglund, Johan;
- Kaminsky, Ronald;
- Kerboeuf, Dominique;
- Küttler, Ulla;
- Papadopoulos, Elias;
- Posedi, Janez;
- Small, John;
- Várady, Marián;
- Vercruysse, Jozef
Publication type:
Article
The Cyclooctadepsipeptide Anthelmintic Emodepside Differentially Modulates Nematode, Insect and Human Calcium-Activated Potassium (SLO) Channel Alpha Subunits.
Published in:
PLoS Neglected Tropical Diseases, 2015, v. 9, n. 10, p. 1, doi. 10.1371/journal.pntd.0004062
By:
- Crisford, Anna;
- Ebbinghaus-Kintscher, Ulrich;
- Schoenhense, Eva;
- Harder, Achim;
- Raming, Klaus;
- O’Kelly, Ita;
- Ndukwe, Kelechi;
- O’Connor, Vincent;
- Walker, Robert J.;
- Holden-Dye, Lindy
Publication type:
Article
Praziquantel – 50 Years of Research.
Published in:
ChemMedChem, 2023, v. 18, n. 12, p. 1, doi. 10.1002/cmdc.202300154
By:
- Waechtler, Andreas;
- Cezanne, Bertram;
- Maillard, David;
- Sun, Rui;
- Wang, Shaofang;
- Wang, Jihua;
- Harder, Achim
Publication type:
Article
Phylogenetic Characterization of β-Tubulins and Development of Pyrosequencing Assays for Benzimidazole Resistance in Cattle Nematodes.
Published in:
PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0070212
By:
- Demeler, Janina;
- Krüger, Nina;
- Krücken, Jürgen;
- von der Heyden, Vera C.;
- Ramünke, Sabrina;
- Küttler, Ursula;
- Miltsch, Sandra;
- López Cepeda, Michael;
- Knox, Malcolm;
- Vercruysse, Jozef;
- Geldhof, Peter;
- Harder, Achim;
- von Samson-Himmelstjerna, Georg
Publication type:
Article
Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration.
Published in:
PLoS Pathogens, 2021, v. 17, n. 7, p. 1, doi. 10.1371/journal.ppat.1009682
By:
- Krücken, Jürgen;
- Holden-Dye, Lindy;
- Keiser, Jennifer;
- Prichard, Roger K.;
- Townson, Simon;
- Makepeace, Benjamin L.;
- Hübner, Marc P.;
- Hahnel, Steffen R.;
- Scandale, Ivan;
- Harder, Achim;
- Kulke, Daniel
Publication type:
Article
A γ-Lactone Form Nafuredin, Nafuredin-γ, also Inhibits Helminth Complex I.
Published in:
Journal of Antibiotics, 2005, v. 58, n. 1, p. 50, doi. 10.1038/ja.2005.5
By:
- Shiomi, Kazuro;
- Ui, Hideaki;
- Suzuki, Hideaki;
- Hatano, Hiroko;
- Nagamitsu, Tohru;
- Takano, Daisuke;
- Miyadera, Hiroko;
- Yamashita, Tetsuo;
- Kita, Kiyoshi;
- Miyoshi, Hideto;
- Harder, Achim;
- Tomoda, Hiroshi;
- Ōmura, Satoshi
Publication type:
Article
SLO-1-Channels of Parasitic Nematodes Reconstitute Locomotor Behaviour and Emodepside Sensitivity in Caenorhabditis elegans slo-1 Loss of Function Mutants.
Published in:
PLoS Pathogens, 2011, v. 7, n. 4, p. 1, doi. 10.1371/journal.ppat.1001330
By:
- Welz, Claudia;
- Krüger, Nina;
- Schniederjans, Monika;
- Miltsch, Sandra M.;
- Krücken, Jürgen;
- Guest, Marcus;
- Holden-Dye, Lindy;
- Harder, Achim;
- Samson-Himmelstjerna, Georg von
Publication type:
Article
Synthesis of anthemintically active N-methylated amidoxime analogues of the cyclic octadepsipeptide PF1022A.
Published in:
Pest Management Science, 2002, v. 58, n. 12, p. 1205, doi. 10.1002/ps.590
By:
- Jeschke, Peter;
- Harder, Achim;
- von Samson-Himmelstjerna, Georg;
- Etzel, Winfried;
- Gau, Wolfgang;
- Thielking, Gerhard;
- Bonse, Gerhard
Publication type:
Article
Characterization of the Ca2+-Gated and Voltage-Dependent K+-Channel Slo-1 of Nematodes and Its Interaction with Emodepside.
Published in:
PLoS Neglected Tropical Diseases, 2014, v. 8, n. 12, p. 1, doi. 10.1371/journal.pntd.0003401
By:
- Kulke, Daniel;
- von Samson-Himmelstjerna, Georg;
- Miltsch, Sandra M.;
- Wolstenholme, Adrian J.;
- Jex, Aaron R.;
- Gasser, Robin B.;
- Ballesteros, Cristina;
- Geary, Timothy G.;
- Keiser, Jennifer;
- Townson, Simon;
- Harder, Achim;
- Krücken, Jürgen
Publication type:
Article
Characterization of the Ca2+-Gated and Voltage-Dependent K+-Channel Slo-1 of Nematodes and Its Interaction with Emodepside.
Published in:
PLoS Neglected Tropical Diseases, 2014, v. 8, n. 12, p. 1, doi. 10.1371/journal.pntd.0003401
By:
- Kulke, Daniel;
- von Samson-Himmelstjerna, Georg;
- Miltsch, Sandra M.;
- Wolstenholme, Adrian J.;
- Jex, Aaron R.;
- Gasser, Robin B.;
- Ballesteros, Cristina;
- Geary, Timothy G.;
- Keiser, Jennifer;
- Townson, Simon;
- Harder, Achim;
- Krücken, Jürgen
Publication type:
Article
Efficacy of Cyclooctadepsipeptides and Aminophenylamidines against Larval, Immature and Mature Adult Stages of a Parasitologically Characterized Trichurosis Model in Mice.
Published in:
PLoS Neglected Tropical Diseases, 2014, v. 8, n. 2, p. 1, doi. 10.1371/journal.pntd.0002698
By:
- Kulke, Daniel;
- Krücken, Jürgen;
- Harder, Achim;
- von Samson-Himmelstjerna, Georg
Publication type:
Article
Efficacy of Cyclooctadepsipeptides and Aminophenylamidines against Larval, Immature and Mature Adult Stages of a Parasitologically Characterized Trichurosis Model in Mice.
Published in:
PLoS Neglected Tropical Diseases, 2014, v. 8, n. 2, p. 1, doi. 10.1371/journal.pntd.0002698
By:
- Kulke, Daniel;
- Krücken, Jürgen;
- Harder, Achim;
- von Samson-Himmelstjerna, Georg
Publication type:
Article
Synthesis and anthelmintic activity of thioamide analogues of cyclic octadepsipeptides such as PF1022A.
Published in:
Pest Management Science, 2001, v. 57, n. 11, p. 1000, doi. 10.1002/ps.382
By:
- Jeschke, Peter;
- Harder, Achim;
- Etzel, Winfried;
- Gau, Wolfgang;
- Thielking, Gerhard;
- Bonse, Gerhard;
- Iinuma, Katsuharu
Publication type:
Article
Amphiphilic Cationic Drugs and Phospholipids Influence the Activities of β-Galactosidase and β-Glucosidase from Liver Lysosomal Fraction of Untreated Rats.
Published in:
Biological Chemistry, 1985, v. 366, n. 1, p. 189
By:
- HARDER, Achim;
- DODT, Gabi;
- DEBUCH, Hildegard
Publication type:
Article

Found: 17

Activation of transient receptor potential channel Sm.(Schistosoma mansoni)TRPMPZQ by PZQ, enhanced Ca++ influx, spastic paralysis, and tegumental disrupture—the deadly cascade in parasitic schistosomes, other trematodes, and cestodes.

In vitro efficacy of cyclooctadepsipepdtides and aminophenylamidines alone and in combination against third-stage larvae and adult worms of Nippostrongylus brasiliensis and first-stage larvae of Trichinella spiralis.

The Putative Cyclooctadepsipeptide Receptor Depsiphilin of the Canine Hookworm Ancylostoma caninum.

Standardization of the egg hatch test for the detection of benzimidazole resistance in parasitic nematodes.

The Cyclooctadepsipeptide Anthelmintic Emodepside Differentially Modulates Nematode, Insect and Human Calcium-Activated Potassium (SLO) Channel Alpha Subunits.

Praziquantel – 50 Years of Research.

Phylogenetic Characterization of β-Tubulins and Development of Pyrosequencing Assays for Benzimidazole Resistance in Cattle Nematodes.

Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration.

A γ-Lactone Form Nafuredin, Nafuredin-γ, also Inhibits Helminth Complex I.

SLO-1-Channels of Parasitic Nematodes Reconstitute Locomotor Behaviour and Emodepside Sensitivity in Caenorhabditis elegans slo-1 Loss of Function Mutants.

Synthesis of anthemintically active N-methylated amidoxime analogues of the cyclic octadepsipeptide PF1022A.

Characterization of the Ca<sup>2+</sup>-Gated and Voltage-Dependent K<sup>+</sup>-Channel Slo-1 of Nematodes and Its Interaction with Emodepside.

Characterization of the Ca<sup>2+</sup>-Gated and Voltage-Dependent K<sup>+</sup>-Channel Slo-1 of Nematodes and Its Interaction with Emodepside.

Efficacy of Cyclooctadepsipeptides and Aminophenylamidines against Larval, Immature and Mature Adult Stages of a Parasitologically Characterized Trichurosis Model in Mice.

Efficacy of Cyclooctadepsipeptides and Aminophenylamidines against Larval, Immature and Mature Adult Stages of a Parasitologically Characterized Trichurosis Model in Mice.

Synthesis and anthelmintic activity of thioamide analogues of cyclic octadepsipeptides such as PF1022A.

Amphiphilic Cationic Drugs and Phospholipids Influence the Activities of β-Galactosidase and β-Glucosidase from Liver Lysosomal Fraction of Untreated Rats.