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- Title
Molecular Architecture and Biomedical Leads of Terpenes from Red Sea Marine Invertebrates.
- Authors
Hegazy, Mohamed Elamir F.; Mohamed, Tarik A.; Alhammady, Montaser A.; Shaheen, Alaa M.; Reda, Eman H.; Elshamy, Abdelsamed I.; Aziz, Mina; Paré, Paul W.
- Abstract
Marine invertebrates including sponges, soft coral, tunicates, mollusks and bryozoan have proved to be a prolific source of bioactive natural products. Among marine-derived metabolites, terpenoids have provided a vast array of molecular architectures. These isoprenoid-derived metabolites also exhibit highly specialized biological activities ranging from nerve regeneration to blood-sugar regulation. As a result, intense research activity has been devoted to characterizing invertebrate terpenes from both a chemical and biological standpoint. This review focuses on the chemistry and biology of terpene metabolites isolated from the Red Sea ecosystem, a unique marine biome with one of the highest levels of biodiversity and specifically rich in invertebrate species.
- Subjects
MARINE natural products; MARINE invertebrates; TERPENES synthesis; BLOOD sugar monitoring; MARINE biodiversity
- Publication
Marine Drugs, 2015, Vol 13, Issue 5, p3154
- ISSN
1660-3397
- Publication type
Article
- DOI
10.3390/md13053154