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- Title
Safety Assessment of Whole and Hulled Djulis (Chenopodium formosanum Koidz).
- Authors
Tuzz-Ying Song; Rong-Rong Chen; Jiunn-Wang Liao; Chen-I Chen; Chien-Lin Chen; Chiu-Yuan Chen
- Abstract
Chenopodium formosanum Koidz is a traditional crop of the aborigines in Taiwan, and is commonly called “Djulis”. Dlulis is rich in nutrients and functional ingredients, and research has shown that it has various biological effects, such as decrease of cholesterol and enhancement of immunity. Because Djulis is not listed as a food crop in many countries including Taiwan, it is difficult to promote its cultivation and product development. Therefore, there is an urgent need to determine the safe intake level of Djulis by safety assessment. In this study, male and female rats were divided into 8 groups: blank (AIN-76A diet), control (high-gluten flour), low-, medium-, and high-dose whole Djulis (WD) or hulled Djulis (HD). To prepare the diets, WD or HD was pre-mixed with 2× water, heated, mixed with rat chow, then dried to form 7.5, 14.1, and 25.2% WD or HD diets. Results revealed that after feeding for 28 days, the behavior, organ/tissue weights, histological stain, and blood and urine biochemistry of rats fed WD or HD were all in the normal range and not statistically different from those of rats fed the blank or control diets. However, plasma glutamic pyruvic transaminase activities in both female and male rats of high-dose HD groups were significantly increased, as compared with those of rats fed the blank or control groups, and were higher than the normal range, suggesting that H-HD may potentially cause liver damage. Based on the medium dose (14.1%), a safe daily intake of HD for human adults is estimated to be 70.5 g (dry weight) while the safe daily intake for WD is at least beyond 126 g (estimated based on 25.2% WD or higher intake).
- Publication
Taiwanese Journal of Agricultural Chemistry & Food Science, 2016, Vol 54, Issue 6, p247
- ISSN
1605-2471
- Publication type
Article