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- Title
Local Allergic Rhinitis in Adult Patients with Chronic Nasal Symptoms.
- Authors
Krajewska-Wojtys, Anna; Jarzab, Jerzy; Zawadzińska, Kamila; Pyrkosz, Katarzyna; Bozek, Andrzej
- Abstract
Background: Local allergic rhinitis (LAR) remains an underdiagnosed condition characterized by the local production of IgE antibodies during the natural exposure to aeroallergens. The prevalence of LAR in adult patients with a previous diagnosis of non-AR was assessed. Material and Methods: Eighty-four patients with perennial nasal allergy symptoms but a negative skin prick test and specific IgE antibodies against common inhalant allergens were included in the study. Nasal provocation tests were performed with the inhalant allergens Dermatophagoides pteronyssinus , Alternaria, and cat allergen, followed by the detection of nasal-specific IgE antibodies in the lavage during the challenge. Results: LAR was confirmed in 21 (25%) study patients. In the remaining 63 (75%) patients, non-AR was diagnosed. In addition, LAR was found following exposure to D. pteronyssinus in 19 (22.6%) patients, Alternaria in 3 (3.6%) patients, and the cat allergen in 1 (1.2%) patient. In 2 patients, concomitant allergies to D. pteronyssinus and Alternaria were observed. Conclusion: LAR can be a form of chronic perennial rhinitis that has previously been considered to be non-AR.
- Subjects
ALLERGIC rhinitis; RHINITIS; NOSE diseases; ATOPY; INFLAMMATION
- Publication
International Archives of Allergy & Immunology, 2017, Vol 173, Issue 3, p165
- ISSN
1018-2438
- Publication type
Article
- DOI
10.1159/000478656