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- Title
Immature Teratoma Ovarium in Young Women: Two Case Reports and Literature Reviews.
- Authors
Ekawati, Ni Putu; Juli Sumadi, I. Wayan; Mahastuti, Ni Made; Wirya Santosa, I. Made
- Abstract
Immature teratoma is teratoma that contains several variations of immature tissue, including primitive forms and embryoid bodies. This type of neoplasm is rare, accounting for less than 1 % of all ovarian tumors and 20 % of malignant germ cell tumors in the ovarium. The incidence occurs in young women usually in the first two decades of life and rarely occurs in postmenopausal women. Two cases of immature teratoma were reported in women aged 16 and 25 with abdominal swelling and lower abdominal pain. Macroscopic examination of the first case revealed some solid, some cystic, containing hair, bones, teeth, and dermal plaque. Routine histopathologic examination showed tumors consisting of ectoderm, mesoderm, and endoderm components, as well as an immature neuroectodermal component with a pseudorosette. Macroscopic examination of the first case revealed a solid mass, containing bones and hair. The tumour consists of ectoderm, mesoderm, and endoderm components, in the form of immature cartilage, immature mesenchymal and neuroectodermal cells that form tubular structures, and some rosette-shaped features. The primitive neuroectodermal cells were oval-shaped, narrow cytoplasm with an increased N/C ratio, and the hyperchromatic nucleus was arranged in a stratified way. Based on clinical data and histopathologic examination, those patients were diagnosed as having grade 2 and grade 3 immature teratoma.
- Subjects
TERATOMA; OVARIAN tumors; MESODERM; ENDODERM; DATA analysis
- Publication
Gaceta Médica de Caracas, 2022, Vol 130, pS7
- ISSN
0367-4762
- Publication type
Article
- DOI
10.47307/GMC.2022.130.s1.3