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- Title
Efficacy of trans-cinnamaldehyde against Psoroptes cuniculi in vitro.
- Authors
Shen, Fengge; Xing, Mingxun; Liu, Lihui; Tang, Xudong; Wang, Wei; Wang, Xiaohong; Wu, Xiuping; Wang, Xuelin; Wang, Xinrui; Wang, Guangming; Zhang, Junhui; Li, Lei; Zhang, Jiyu; Yu, Lu
- Abstract
The acaricidal activity of trans-cinnamaldehyde was evaluated in vitro on Psoroptes cuniculi. In this study, different concentrations of trans-cinnamaldehyde were tested, and the observed mites mortality was compared with that observed in untreated and treated (Acacerulen R®) controls. The morphological changes in P. cuniculi treated with trans-cinnamaldehyde were examined with light microscopy. By the analysis of variance one-way test, up to 8 μg/ml of trans-cinnamaldehyde gave highly significant ( P < 0.01) percentages of mite mortality compared with the untreated controls, but only up to 256 μg/ml, it showed the same efficacy of Acacerulen R®. At the same time, a bioassay was conducted by exposing mites to varying doses of trans-cinnamaldehyde in vitro cultures. The resulting data were analyzed by using a time-dose-mortality modeling technique, yielding the parameters for time and dose effects of P. cuniculi. The β value was 2.01, indicating that trans-cinnamaldehyde had a good activity to kill P. cuniculi adults. Based on the time-dose-mortality relationships fitted and the virulence indices estimated, trans-cinnamaldehyde is a promising microbial agent for mites control.
- Subjects
PSOROPTES; ACARICIDES; MITES; MICROSCOPY; ANALYSIS of variance; BIOLOGICAL assay; MICROBIAL virulence
- Publication
Parasitology Research, 2012, Vol 110, Issue 4, p1321
- ISSN
0932-0113
- Publication type
Article
- DOI
10.1007/s00436-012-2816-y