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- Title
Comparison of <sup>60</sup>Cobalt and <sup>192</sup>Iridium Sources in High Dose Rate Afterloading Brachytherapy.
- Authors
Jürgen Richter; Kurt Baier; Michael Flentje
- Abstract
Purpose:Â Â 60Co sources with dimensions identical to those of 192Ir have recently been made available in clinical brachytherapy. A longer half time reduces demands on logistics and quality assurance and perhaps costs. Material and Methods:Â Â Comparison of the physical properties of 60Co and 192Ir with regard to brachytherapy. Results:Â Â Required activities for the same air kerma rate are lower by a factor of 2.8 for 60Co. Differential absorption in tissues of different densities can be neglected. Monte Carlo calculations demonstrate that integral dose due to radial dose fall off is higher for 192Ir in comparison to 60Co within the first 22 cm from the source (normalization at 1 cm). At larger distances this relationship is reversed. Conclusion:Â Â Clinical examples for intracavitary and interstitial applications however, show practically identical dose distributions in the treatment volume.
- Subjects
RADIOISOTOPE brachytherapy; TISSUES; SURGERY; DRUG dosage
- Publication
Strahlentherapie und Onkologie, 2008, Vol 184, Issue 4, p187
- ISSN
0179-7158
- Publication type
Article
- DOI
10.1007/s00066-008-1684-y