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- Title
New opportunities for dosimetric approach in patients with differentiated thyroid cancer.
- Authors
Piscopo, Leandra; Zampella, Emilia; Klain, Michele
- Abstract
This document discusses the use of radioactive iodine (RAI) therapy in patients with differentiated thyroid cancer (DTC). RAI therapy is commonly used as a treatment option for intermediate and high-risk DTC patients. The therapy can be used for remnant ablation, adjuvant therapy, and metastatic treatment. In pediatric patients, DTC is rare but shows a more aggressive behavior. The document highlights the importance of preserving radiosensitive tissues and reducing complications related to radiation exposure. The dosimetric approach, which aims to optimize the therapeutic effect while minimizing exposure to healthy organs, is discussed. A recent observational study analyzed the adsorbed dose to healthy organs in DTC patients treated with RAI. The study found that dosimetry may help in optimizing and personalizing RAI treatment in DTC patients. However, differences in acquisition protocols and therapy planning among different centers may affect dosimetry estimation. Further multicenter studies are needed to establish a solid foundation for the dosimetric approach in DTC patients.
- Subjects
THYROID cancer; MEDICAL dosimetry; SECONDARY primary cancer; THYROID gland; CANCER patients
- Publication
European Journal of Nuclear Medicine & Molecular Imaging, 2024, Vol 51, Issue 2, p330
- ISSN
1619-7070
- Publication type
Article
- DOI
10.1007/s00259-023-06473-0