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- Title
Routine Prophylactic Central Neck Dissection May Not Obviously Reduce Lateral Neck Recurrence for Papillary Thyroid Microcarcinoma.
- Authors
Xu, Siyuan; Liu, Wensheng; Zhang, Zongmin; Liu, Yang; Xu, Zhengang; Liu, Jie
- Abstract
<bold>Background: </bold>The role of routine prophylactic central compartment neck dissection (pCCND) for papillary thyroid microcarcinoma (PTMC) remains controversial. The lateral neck recurrence-free survival (LRFS) advantages achieved by pCCND are still under investigation.<bold>Methods: </bold>The records of 2,074 consecutive patients with papillary thyroid carcinoma (PTC) at the time of surgery from 1996 to 2009 were retrospectively reviewed. A total of 611 consecutive patients were included in the final analyses. We used R version 3.5.1 to match patients with total thyroidectomy (TT)/lobectomy + pCCND with patients with TT/lobectomy alone and analyzed the following factors with a potential influence: age at diagnosis, sex, extrathyroid extension, and primary tumor multifocality and bilaterality. LRFS was analyzed. Moreover, the data were reanalyzed after separating the pairs of patients with pN1a from those with pN0.<bold>Results: </bold>We were able to select 159 pairs sharing the major prognostic risk factors as listed. Overall, there was no difference in the LRFS, although patients with pCCND more often had recurrence. Moreover, the central lymph node metastasis status had no significant influence on the risk of recurrence.<bold>Conclusion: </bold>Routine pCCND was not a protective factor for LRFS in PTMC patients with cN0. The difference in LRFS between pN0 and pN1a was not statistically significant (p > 0.05).
- Subjects
NECK dissection; PAPILLARY carcinoma; THYROID cancer; NECK; LYMPH nodes
- Publication
ORL, 2019, Vol 81, Issue 2/3, p73
- ISSN
0301-1569
- Publication type
journal article
- DOI
10.1159/000497407