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- Title
Chemistry: Disulphide dichotomies.
- Abstract
The article highlights a study which measured the quantity a bond between two atoms stretches in the transition state in a chemical reaction. It mentions that Sri Rama Koti Ainavarapu and colleagues developed a force clamp technique to use in single-molecule force spectroscopy, which they held onto individual molecules and stretched them to trigger the reduction of a disulphide bond in a protein, invoking the transition state of the reaction. The researchers then measure the distance between the sulphur atoms as they stretched apart.
- Subjects
SULFUR; ATOMS; MOLECULES; CHEMICAL reactions; SULFUR bonding; SPECTRUM analysis; CHEMICAL processes; PHYSICAL &; theoretical chemistry; CHEMICAL research
- Publication
Nature, 2008, Vol 453, Issue 7193, p261
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/453261d