We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Bending around the BAR.
- Authors
Pickett, James
- Abstract
The article reports on the study which focuses on the structure of the F-BAR (Bin-amphiohysin-Rvs) protein domain, which offers insights into how the crescent-shaped modules drive membrame remodelling during endocytosis. The researchers discovered that enforcing their curved shape onto membranes, F-BAR domains oligomerize into filaments which wind around the membrane to induce curvature. Moreover, F-BAR domains recognize the shallow curvature of clathrin-coated pits to drive membrane.
- Subjects
ENDOCYTOSIS; ABSORPTION (Physiology); CELL physiology; MEMBRANE proteins; CURVATURE
- Publication
Nature Reviews Molecular Cell Biology, 2007, Vol 8, Issue 7, p514
- ISSN
1471-0072
- Publication type
Article
- DOI
10.1038/nrm2206