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- Title
Generation of a tree shrew breast cancer model using lentivirus expressing PIK3CA-H1047R.
- Authors
Li Zeng; Hong-Yan Zhang; Chuan-Yu Yang; Zhuo Cheng; Qiu-Yun Jiang; Yao Luo; Yi Li; Fu-Bing Li; Ce-Shi Chen
- Abstract
The article discusses research which overexpressed the PIK3CA-H1047R gene in the mammary epithelial cells of tree shrews using a lentivirus to induce breas tumors in order to provide a new animal model of breast cancer. Topics covered include the pathological characteristics of the tumors, the tumor incubation period and incidence rate, and the implications of the research findings on the study of breast cancer mechanisms and the evaluation of novel drugs.
- Subjects
BREAST; SHREWS; BREAST cancer; LENTIVIRUSES
- Publication
Zoological Research, 2023, Vol 44, Issue 1, p94
- ISSN
2095-8137
- Publication type
Article
- DOI
10.24272/j.issn.2095-8137.2022.240