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- Title
Neurological presentations of Bartonella henselae infection.
- Authors
Canneti, B.; Cabo-López, I.; Puy-Núñez, A.; García García, J. C.; Cores, F. J.; Trigo, M.; Suárez-Gil, A. P.; Rodriguez-Regal, A.
- Abstract
<bold>Objective: </bold>Neurological symptoms in patients with cat-scratch disease (CSD) have been rarely reported. The aim of this study is to analyze the frequency of neurological CSD (NCSD) and describe the disease clinical presentation, management and outcome.<bold>Material and Methods: </bold>We retrospectively selected patients with a CSD syndrome and Bartonella IgG titers > 1:256. Data regarding epidemiological, clinical, management, and follow-up features were analyzed and discussed. A comparison between NCSD and non-neurological CSD (NNCSD) was established.<bold>Results: </bold>Thirty-nine CSD patients were selected. NCSD frequency was 10.25%. No children were found affected in the NCSD group. A 65.7% of NNCSD and the entirety of the NCSD group had a history of cat exposure. Immunosuppression was only present in the NNCSD group (8.6%). NCSD presentations were as follows: isolated aseptic meningitis (25%), neuroretinitis (50%), and isolated optic neuritis (25%). A greater proportion of patients in the NCSD group had fever and raised levels of acute phase reactants and white blood cells. 85.7% of NNCSD had a complete recovery, whereas only 50% of the NCSD patients experienced a full recovery.<bold>Conclusion: </bold>NCSD may be a distinctive group compared to NNCSD due to its later age of presentation, the more intense systemic response, and the poorer outcome.
- Subjects
OPTIC neuritis; ACUTE phase proteins; LEUCOCYTES; BARTONELLA infections; BARTONELLA henselae; MENINGITIS; FEVER; ANTIBIOTICS; COMPARATIVE studies; GRAM-negative bacteria; RESEARCH methodology; MEDICAL cooperation; RESEARCH; RETINA; CAT-scratch disease; EVALUATION research; TREATMENT effectiveness; RETROSPECTIVE studies
- Publication
Neurological Sciences, 2019, Vol 40, Issue 2, p261
- ISSN
1590-1874
- Publication type
journal article
- DOI
10.1007/s10072-018-3618-5