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- Title
Cytostatic Therapy on Tumor Bearing Mice: Biochemical and Hematological Aspects.
- Authors
Anghelache, Laurenţiu; Marinescu, Bogdan; Isvoranu, Gheorghiţa; Crînganu, Dan; Niculae, Andrei; Bratu, Ovidiu
- Abstract
In this study we used a carcinoma and melanoma allograft experimental model on C57BL/6 mice. We administrated three chemotherapy substances (ifosfamide, carboplatin, epirubicin hydrochloride), in order to observe changes of the biochemical and hematological parameters. Additionally, the evolution of tumor mass was measured during the experiment. The study was conducted on a total of 77 mice with a weigh between 20 - 22 g, during two month.
- Subjects
ANTINEOPLASTIC agents; BIOMARKERS
- Publication
Medicina Moderna, 2018, Vol 25, Issue 3, p26
- ISSN
1223-0472
- Publication type
Article