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- Title
Restoration of Normoxia by Ozone Therapy May Control Neoplastic Growth: A Review and a Working Hypothesis.
- Authors
Bocci, Velio; Larini, Alessandra; Micheli, Vanna
- Abstract
In contrast to normal tissues, tumors thrive in hypoxic environments. This appears to be because they canmetastasize and secrete angiopoietins for enhancing neoangiogenesis and further tumor spread. Thus, duringchronic ischemia, normal tissues tend to die, while neoplasms tend to grow. During the past two decades, ithas been shown in arteriopathic patients that ozonated autohemotherapy is therapeutically useful because it increasesoxygen delivery in hypoxic tissues, leading to normoxia. Although several oxygenation approaches havebeen tested, none is able to restore normoxia permanently in patients with cancer. We postulate that a prolongedcycle of ozonated autohemotherapy may correct tumor hypoxia, lead to less aggressive tumor behavior, andrepresent a valid adjuvant during or after chemo- or radiotherapy. Moreover, it may re-equilibrate the chronicoxidative stress and reduce fatigue.
- Subjects
TISSUES; TUMORS; CANCER patients; ISCHEMIA; CEREBRAL anoxia; IMMUNOLOGICAL adjuvants
- Publication
Journal of Alternative & Complementary Medicine, 2005, Vol 11, Issue 2, p257
- ISSN
1075-5535
- Publication type
Article
- DOI
10.1089/acm.2005.11.257